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Publication : A zebrafish homolog of the serum response factor gene is highly expressed in differentiating embryonic myocytes.

First Author  Vogel AM Year  1999
Journal  Mech Dev Volume  81
Issue  1-2 Pages  217-21
PubMed ID  10330504 Mgi Jnum  J:54210
Mgi Id  MGI:1334794 Doi  10.1016/s0925-4773(98)00245-7
Citation  Vogel AM, et al. (1999) A zebrafish homolog of the serum response factor gene is highly expressed in differentiating embryonic myocytes. Mech Dev 81(1-2):217-21
abstractText  Serum response factor (SRF) was identified as an activity binding upon serum stimulation of HeLa cells to a motif known as the serum response element in the c-fos promoter. This element is also found in the regulatory regions of many muscle-specific genes. We have characterized srf expression during early zebrafish embryogenesis. In addition to low-level expression in many or even all cells, elevated levels of srf RNA and protein are transiently expressed in skeletal muscle lineages during their differentiation.
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