First Author | Vogel AM | Year | 1999 |
Journal | Mech Dev | Volume | 81 |
Issue | 1-2 | Pages | 217-21 |
PubMed ID | 10330504 | Mgi Jnum | J:54210 |
Mgi Id | MGI:1334794 | Doi | 10.1016/s0925-4773(98)00245-7 |
Citation | Vogel AM, et al. (1999) A zebrafish homolog of the serum response factor gene is highly expressed in differentiating embryonic myocytes. Mech Dev 81(1-2):217-21 |
abstractText | Serum response factor (SRF) was identified as an activity binding upon serum stimulation of HeLa cells to a motif known as the serum response element in the c-fos promoter. This element is also found in the regulatory regions of many muscle-specific genes. We have characterized srf expression during early zebrafish embryogenesis. In addition to low-level expression in many or even all cells, elevated levels of srf RNA and protein are transiently expressed in skeletal muscle lineages during their differentiation. |