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Publication : Notch around the clock.

First Author  Pourquié O Year  1999
Journal  Curr Opin Genet Dev Volume  9
Issue  5 Pages  559-65
PubMed ID  10508694 Mgi Jnum  J:58310
Mgi Id  MGI:1347198 Doi  10.1016/s0959-437x(99)00011-8
Citation  Pourquie O (1999) Notch around the clock. Curr Opin Genet Dev 9(5):559-65
abstractText  The establishment of a segmental pattern within the vertebrate body plan is achieved during embryogenesis by the somitogenesis process. Two molecular systems have been implicated in this phenomenon: a molecular clock linked to vertebrate segmentation and the Notch signalling pathway. Rhythmic expression of the Lunatic Fringe gene in the presomitic mesoderm has now provided a link between these two systems.
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