| First Author | Cohen MM Jr | Year | 2002 |
| Journal | Am J Med Genet | Volume | 109 |
| Issue | 1 | Pages | 1-15 |
| PubMed ID | 11932986 | Mgi Jnum | J:75686 |
| Mgi Id | MGI:2177368 | Doi | 10.1002/ajmg.10258 |
| Citation | Cohen MM Jr, et al. (2002) Teratogenesis of holoprosencephaly. Am J Med Genet 109(1):1-15 |
| abstractText | Teratogenic causes of holoprosencephaly are critically assessed. A brief general review of holoprosencephaly is followed by four tables summarizing etiologic factors. Subjects evaluated here include: 1) maternal diabetes; 2) ethyl alcohol; 3) retinoic acid; 4) mutated genes and teratogens involving the sonic hedgehog signaling network and cholesterol biosynthesis; and 5) cholesterol trafficking, sterol adducts, target tissue response, and sterol sensing domain. |
