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Publication : Functional peculiarities of MAP2 in DBA/2J inbred mice as a component of genetic predisposition to seizures.

First Author  Chulanova TA Year  2001
Journal  Bull Exp Biol Med Volume  132
Issue  5 Pages  1058-61
PubMed ID  11865321 Mgi Jnum  J:75898
Mgi Id  MGI:2178009 Doi  10.1023/a:1017960306927
Citation  Chulanova TA, et al. (2001) Functional peculiarities of MAP2 in DBA/2J inbred mice as a component of genetic predisposition to seizures. Bull Exp Biol Med 132(5):1058-61
abstractText  We compared the content of high molecular microtubule-associated protein-2 and its phosphorylation by cAMP- and Ca(2+)/calmodulin-dependent protein kinases in the brain of DBA/2J and C57Bl/6 inbred mice. The revealed differences in protein content and phosphorylation can be attributed to the mechanisms mediating audiogenic seizures in DBA/2J mice and to differential sensitivity of these inbred lines to seizure-inducing factors.
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