| First Author | Kumánovics A | Year | 2002 |
| Journal | Immunogenetics | Volume | 54 |
| Issue | 7 | Pages | 479-89 |
| PubMed ID | 12389096 | Mgi Jnum | J:80482 |
| Mgi Id | MGI:2445917 | Doi | 10.1007/s00251-002-0494-0 |
| Citation | Kumanovics A, et al. (2002) QUOD ERAT FACIENDUM: sequence analysis of the H2-D and H2-Q regions of 129/SvJ mice. Immunogenetics 54(7):479-89 |
| abstractText | The H2-D and -Q regions of the mouse major histocompatibility complex ( Mhc or H2) have been sequenced from strain 129/SvJ (haplotype bc), revealing a D/Q region different from all other investigated haplotypes, including the closely related b haplotype. The 300-kb class I-rich region consists of the classical class I, H2-D, and 11 non-classical class I genes. The Q region was formed by two series of tandem duplications. Comparison of the segment between the D and Q1 genes with the H2-K region provides evidence that class I genes were translocated from the K region to the D region, and gives a new explanation for the weak locus specificity of the H-Kand H2-Dalleles. |
