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Publication : Pair-wise linear and 3D nonlinear relationships between the liver antioxidant enzyme activities and the rate of body oxygen consumption in mice.

First Author  Muradian KK Year  2002
Journal  Free Radic Biol Med Volume  33
Issue  12 Pages  1736-9
PubMed ID  12488141 Mgi Jnum  J:81298
Mgi Id  MGI:2448849 Doi  10.1016/s0891-5849(02)01196-6
Citation  Muradian KK, et al. (2002) Pair-wise linear and 3D nonlinear relationships between the liver antioxidant enzyme activities and the rate of body oxygen consumption in mice. Free Radic Biol Med 33(12):1736-9
abstractText  Relationships between the rate of body oxygen consumption (VO(2)) and the liver key antioxidant enzyme activities were assessed in female CBA mice. The pair-wise linear regression and correlation demonstrated significant correlative links between VO(2) and activity of catalase (CAT). Nonlinear 3D plotting revealed a complementary pattern of CAT and glutathione peroxidase (GP) relation. CAT activity was elevated in mice with proportionally high VO(2) and superoxide dismutase (SOD), whereas GP activity was high in animals with low or disproportional VO(2) and SOD.
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