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Publication : Expression of opsin genes early in ocular development of humans and mice.

First Author  Tarttelin EE Year  2003
Journal  Exp Eye Res Volume  76
Issue  3 Pages  393-6
PubMed ID  12573668 Mgi Jnum  J:82333
Mgi Id  MGI:2652301 Doi  10.1016/s0014-4835(02)00300-7
Citation  Tarttelin EE, et al. (2003) Expression of opsin genes early in ocular development of humans and mice. Exp Eye Res 76(3):393-6
abstractText  We have compared the onsets of expression of the classical visual opsins with those of the non-rod, non-cone opsins in foetal and post-natal eye tissue from mice and humans. Mouse Rgr-opsin, peropsin, encephalopsin and melanopsin are all expressed in foetal development by E11.5, unlike the murine rod and cone opsins that exhibit post-natal expression, e.g. P1 for ultraviolet cone opsin and P5 for rod opsin. Human non-rod, non-cone opsins are also all expressed early, by 8.6 weeks post-conception. The implications of these observations are discussed with regard to the possible functions of these opsins at early stages of ocular development.
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