First Author | Tarttelin EE | Year | 2003 |
Journal | Exp Eye Res | Volume | 76 |
Issue | 3 | Pages | 393-6 |
PubMed ID | 12573668 | Mgi Jnum | J:82333 |
Mgi Id | MGI:2652301 | Doi | 10.1016/s0014-4835(02)00300-7 |
Citation | Tarttelin EE, et al. (2003) Expression of opsin genes early in ocular development of humans and mice. Exp Eye Res 76(3):393-6 |
abstractText | We have compared the onsets of expression of the classical visual opsins with those of the non-rod, non-cone opsins in foetal and post-natal eye tissue from mice and humans. Mouse Rgr-opsin, peropsin, encephalopsin and melanopsin are all expressed in foetal development by E11.5, unlike the murine rod and cone opsins that exhibit post-natal expression, e.g. P1 for ultraviolet cone opsin and P5 for rod opsin. Human non-rod, non-cone opsins are also all expressed early, by 8.6 weeks post-conception. The implications of these observations are discussed with regard to the possible functions of these opsins at early stages of ocular development. |