First Author | Esumi H | Year | 1989 |
Journal | Jpn J Cancer Res | Volume | 80 |
Issue | 12 | Pages | 1176-8 |
PubMed ID | 2516847 | Mgi Jnum | J:90311 |
Mgi Id | MGI:3042852 | Doi | 10.1111/j.1349-7006.1989.tb01651.x |
Citation | Esumi H, et al. (1989) Induction of lymphoma in CDF1 mice by the food mutagen, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine. Jpn J Cancer Res 80(12):1176-8 |
abstractText | The mutagenic compound, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP), originally isolated from cooked beef, was tested for carcinogenicity in CDF1 mice of both sexes. When PhIP was given in the diet at a concentration of 0.04%, high incidences and early appearances of lymphomas were observed in both sexes during the 579-day experiment. |