First Author | Broussard DR | Year | 2004 |
Journal | J Virol | Volume | 78 |
Issue | 9 | Pages | 4943-6 |
PubMed ID | 15078980 | Mgi Jnum | J:89248 |
Mgi Id | MGI:3039223 | Doi | 10.1128/JVI.78.9.4943-4946.2004 |
Citation | Broussard DR, et al. (2004) Rorgamma (Rorc) is a common integration site in type B leukemogenic virus-induced T-cell lymphomas. J Virol 78(9):4943-6 |
abstractText | The retrovirus type B leukemogenic virus (TBLV) causes T-cell lymphomas in mice. We have identified the Rorgamma locus as an integration site in 19% of TBLV-induced tumors. Overexpression of one or more Rorgamma isoforms in >77% of the tumors tested may complement apoptotic effects of c-myc overexpression. |