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Publication : Rorgamma (Rorc) is a common integration site in type B leukemogenic virus-induced T-cell lymphomas.

First Author  Broussard DR Year  2004
Journal  J Virol Volume  78
Issue  9 Pages  4943-6
PubMed ID  15078980 Mgi Jnum  J:89248
Mgi Id  MGI:3039223 Doi  10.1128/JVI.78.9.4943-4946.2004
Citation  Broussard DR, et al. (2004) Rorgamma (Rorc) is a common integration site in type B leukemogenic virus-induced T-cell lymphomas. J Virol 78(9):4943-6
abstractText  The retrovirus type B leukemogenic virus (TBLV) causes T-cell lymphomas in mice. We have identified the Rorgamma locus as an integration site in 19% of TBLV-induced tumors. Overexpression of one or more Rorgamma isoforms in >77% of the tumors tested may complement apoptotic effects of c-myc overexpression.
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