First Author | Lampa SJ | Year | 2004 |
Journal | Brain Res Dev Brain Res | Volume | 153 |
Issue | 2 | Pages | 271-4 |
PubMed ID | 15527895 | Mgi Jnum | J:94638 |
Mgi Id | MGI:3513632 | Doi | 10.1016/j.devbrainres.2004.09.005 |
Citation | Lampa SJ, et al. (2004) Ephrin-A5 overexpression degrades topographic specificity in the mouse gluteus maximus muscle. Brain Res Dev Brain Res 153(2):271-4 |
abstractText | Motor neurons project onto specific muscles with a distinct positional bias. We have previously shown using electrophysiological techniques that overexpression of ephrin-A5 degrades this topographic map. Here, we show that positional differences in axon terminal areas, an entirely different parameter of neuromuscular topography, are also eliminated with ephrin-A5 overexpression. Therefore, we now have both morphological and electrophysiological approaches to explore the mechanisms of neuromuscular topography. |