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Publication : P53 and prognosis: new insights and further complexity.

First Author  Vousden KH Year  2005
Journal  Cell Volume  120
Issue  1 Pages  7-10
PubMed ID  15652475 Mgi Jnum  J:95926
Mgi Id  MGI:3528105 Doi  10.1016/j.cell.2004.12.027
Citation  Vousden KH, et al. (2005) P53 and prognosis: new insights and further complexity. Cell 120(1):7-10
abstractText  Despite the massive amount of knowledge that has accumulated about p53, there is still much to learn about its role in tumor suppression. New papers now provide evidence that levels of Mdm2 in humans or presence of mutant forms of p53 in mice can have profound impacts on survival and tumorigenesis. These findings may lead to new diagnostic and therapeutic approaches to treating cancer patients.
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