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Publication : Close linkage of Mdm-1, a gene amplified and overexpressed in a transformed 3T3 cell line, with gamma interferon (Ifg) on chromosome 10 of the mouse.

First Author  Taylor BA Year  1992
Journal  Mamm Genome Volume  3
Issue  12 Pages  700-4
PubMed ID  10712011 Mgi Jnum  J:3520
Mgi Id  MGI:52033 Doi  10.1007/BF00444365
Citation  Taylor BA, et al. (1992) Close linkage of Mdm-1, a gene amplified and overexpressed in a transformed 3T3 cell line, with gamma interferon (Ifg) on Chromosome 10 of the mouse. Mamm Genome 3(12):700-4
abstractText  The Mdm-1 gene was mapped to the distal end of Chromosome (Chr) 10. An extensive series of restriction fragment variants was identified among conventional and exotic inbred strains of mice. Mapping was carried out with recombinant inbred strains and an intersubspecific testcross. No recombinants were observed between Mdm-1 and the gamma interferon locus (Ifg). These two loci appear to be in linkage disequilibrium among inbred strains. Data from the testcross place Mdm-1 approximately 11 centimorgans distal to the steel (Sl) locus. Because of its extensive polymorphism, Mdm-1 is a useful genetic marker for distal Chr 10.
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