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Publication : Building a better model of cancer.

First Author  Marusyk A Year  2006
Journal  Cell Div Volume  1
Pages  24 PubMed ID  17049090
Mgi Jnum  J:117010 Mgi Id  MGI:3695365
Doi  10.1186/1747-1028-1-24 Citation  Marusyk A, et al. (2006) Building a better model of cancer. Cell Div 1:24
abstractText  ABSTRACT: The 2006 Cold Spring Harbor Laboratory meeting on the Mechanisms and Models of Cancer was held August 16-20. The meeting featured several hundred presentations of many short talks (mostly selected from the abstracts) and posters, with the airing of a number of exciting new discoveries. We will focus this meeting review on models of cancer (primarily mouse models), highlighting recent advances in new mouse models that better recapitulate sporadic tumorigenesis, demonstrations of tumor addiction to tumor suppressor inactivation, new insight into senescence as a tumor barrier, improved understanding of the evolutionary paths of cancer development, and environmental/immunological influences on cancer.
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