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Publication : Cell cycle regulatory control for uterine stromal cell decidualization in implantation.

First Author  Das SK Year  2009
Journal  Reproduction Volume  137
Issue  6 Pages  889-99
PubMed ID  19307426 Mgi Jnum  J:150218
Mgi Id  MGI:3849928 Doi  10.1530/REP-08-0539
Citation  Das SK (2009) Cell cycle regulatory control for uterine stromal cell decidualization in implantation. Reproduction 137(6):889-99
abstractText  Uterine stromal cell decidualization is integral to successful embryo implantation, which is a gateway to pregnancy establishment. This process is characterized by stromal cell proliferation and differentiation into decidual cells with polyploidy. The molecular mechanisms that are involved in these events remain poorly understood. The current concept is that locally induced factors with the onset of implantation influence uterine stromal cell proliferation and/or differentiation through modulation of core cell cycle regulators. This review will aim to address the currently available knowledge on interaction between growth factor/homeobox and cell cycle regulatory signaling in the progression of various aspects of decidualization.
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