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Publication : Complexins living up to their name--new light on their role in exocytosis.

First Author  Stein A Year  2009
Journal  Neuron Volume  64
Issue  3 Pages  295-7
PubMed ID  19914176 Mgi Jnum  J:155762
Mgi Id  MGI:4415655 Doi  10.1016/j.neuron.2009.10.026
Citation  Stein A, et al. (2009) Complexins living up to their name--new light on their role in exocytosis. Neuron 64(3):295-7
abstractText  Ca(2+)-dependent exocytosis of synaptic vesicles is mediated by the SNARE proteins synaptobrevin/VAMP, SNAP-25, and syntaxin. SNARE function is controlled by conserved regulatory proteins, including the complexins. In a study by Xue et al. in this issue of Neuron, contradictory data from Drosophila and mouse complexin mutants have been resolved, revealing a complex pattern of facilitatory and inhibitory domains.
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