First Author | Stiess M | Year | 2011 |
Journal | Neuron | Volume | 69 |
Issue | 2 | Pages | 183-5 |
PubMed ID | 21262456 | Mgi Jnum | J:168145 |
Mgi Id | MGI:4887278 | Doi | 10.1016/j.neuron.2011.01.007 |
Citation | Stiess M, et al. (2011) Controlled demolition: smurf1 regulates neuronal polarity by substrate switching. Neuron 69(2):183-5 |
abstractText | During axon specification, growth promoting proteins localize selectively to the growing axon. In this issue of Neuron, Cheng et al. report how selective protein degradation, controlled by a substrate switch of the ubiquitin ligase Smurf1, specifies Par6 and RhoA localization and thereby regulates neuronal polarity. |