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Publication : Visualization of mouse embryo angiogenesis by fluorescence-based staining.

First Author  Liu Y Year  2012
Journal  Methods Mol Biol Volume  843
Pages  79-85 PubMed ID  22222523
Mgi Jnum  J:183122 Mgi Id  MGI:5317506
Doi  10.1007/978-1-61779-523-7_8 Citation  Liu Y, et al. (2012) Visualization of mouse embryo angiogenesis by fluorescence-based staining. Methods Mol Biol 843:79-85
abstractText  The establishment of a blood vessel network is fundamental to embryonic development and plays a critical role in many diseases including coronary heart disease and cancer. Vascular endothelial cells are central players in blood vessel formation and line the inside of the entire blood vessel system. PECAM-1 is expressed in all types of endothelial cells and is therefore a useful marker for the detection of blood vessels. In this manuscript, we describe PECAM-1 staining in whole-mount and sectioned tissues in mouse embryos.
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