| First Author | Minelli A | Year | 2010 |
| Journal | Mitochondrion | Volume | 10 |
| Issue | 4 | Pages | 369-79 |
| PubMed ID | 20230919 | Mgi Jnum | J:192153 |
| Mgi Id | MGI:5464093 | Doi | 10.1016/j.mito.2010.03.004 |
| Citation | Alba M, et al. (2010) Adenosine A(1) receptors contribute to mitochondria vulnerability to pro-oxidant stressors. Mitochondrion 10(4):369-79 |
| abstractText | A(1) adenosine receptors are highly expressed in the central nervous system. Mitochondrial function is a major player in adenosine receptors-mediated effects. Here, by using mice with genetic deletion of the A(1) receptor, we addressed the existence of a relationship between mitochondria functions and adenosine A(1) receptor. Mitochondrial functions and effects of MPP(+) in primary mixed cultures are influenced by the presence of the A(1) receptor, demonstrating, for the first time, the mitochondrial localization of the adenosine A(1) receptor and suggesting a role for this receptor as a mitochondrial vulnerability factor. |
