First Author | Bogolyubova IO | Year | 2014 |
Journal | Tissue Cell | Volume | 46 |
Issue | 6 | Pages | 457-61 |
PubMed ID | 25175035 | Mgi Jnum | J:316195 |
Mgi Id | MGI:6834170 | Doi | 10.1016/j.tice.2014.08.002 |
Citation | Bogolyubova IO, et al. (2014) Immunocytochemical study of YB-1 nuclear distribution in different cell types. Tissue Cell 46(6):457-61 |
abstractText | In the present work we studied the distribution of YB-1 in the nuclei of mouse hepatocytes, early embryos and human skin fibroblasts with the use of light and electron microscopy. To reveal YB-1, we applied rat polyclonal antibody against the C-terminal fragment of YB-1 molecule and rabbit polyclonal antibody against full-length YB-1 molecule. YB-1 distribution patterns varied significantly in different cell types. YB-1 was found to be colocalized with RNA polymerase I in mouse hepatocytes and embryos. Besides, YB-1 was revealed in a population of Cajal bodies in 2-cell mouse embryos but not in other cells studied. |