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Publication : The impact of MITF on melanoma development: news from bench and bedside.

First Author  Roider EM Year  2014
Journal  J Invest Dermatol Volume  134
Issue  1 Pages  16-17
PubMed ID  24352080 Mgi Jnum  J:206391
Mgi Id  MGI:5550182 Doi  10.1038/jid.2013.390
Citation  Roider EM, et al. (2014) The impact of MITF on melanoma development: news from bench and bedside. J Invest Dermatol 134(1):16-7
abstractText  In the current issue, two articles highlight the impact of melanocyte transcription factor (MITF) on melanoma development. In the first, Lister et al. reveal in vivo proof of MITF directly regulating tumor development in BRAF(V600E) melanomas. In the second, Sturm et al. present a clinical trial that emphasizes the importance of the recently discovered E318K MITF germline mutation in patients with multiple primary melanomas.
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