First Author | Nakamura Y | Year | 2013 |
Journal | Biochem Biophys Res Commun | Volume | 441 |
Issue | 1 | Pages | 42-6 |
PubMed ID | 24129192 | Mgi Jnum | J:211525 |
Mgi Id | MGI:5575615 | Doi | 10.1016/j.bbrc.2013.10.014 |
Citation | Nakamura Y, et al. (2013) FABP3 and brown adipocyte-characteristic mitochondrial fatty acid oxidation enzymes are induced in beige cells in a different pathway from UCP1. Biochem Biophys Res Commun 441(1):42-6 |
abstractText | Cold exposure and beta3-adrenergic receptor agonist (CL316,243) treatment induce the production of beige cells, which express brown adipocytes(BA)-specific UCP1 protein, in white adipose tissue (WAT). It remains unclear whether the beige cells, which have different gene expression patterns from BA, express BA-characteristic fatty acid oxidation (FAO) proteins. Here we found that 5 day cold exposure and CL316,243 treatment of WAT, but not CL316,243 treatment of primary adipocytes of C57BL/6J mice, increased mRNA levels of BA-characteristic FAO proteins. These results suggest that BA-characteristic FAO proteins are induced in beige cells in a different pathway from UCP1. |