First Author | Svalina MN | Year | 2014 |
Journal | Cancer Cell | Volume | 26 |
Issue | 2 | Pages | 154-5 |
PubMed ID | 25117705 | Mgi Jnum | J:214599 |
Mgi Id | MGI:5603463 | Doi | 10.1016/j.ccr.2014.07.011 |
Citation | Svalina MN, et al. (2014) YAPping about differentiation therapy in muscle cancer. Cancer Cell 26(2):154-5 |
abstractText | Overcoming a presumed differentiation block in the childhood muscle cancer embryonal rhabdomyosarcoma is often thought to hold promise as an approach to replace cytotoxic chemotherapy with molecularly-targeted differentiation therapies. In this issue of Cancer Cell, Tremblay and colleagues implicate YAP1 and the Hippo signaling pathway in the maintenance of differentiation-arrested and proliferative phenotypes for embryonal rhabdomyosarcoma. |