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Publication : YAPping about differentiation therapy in muscle cancer.

First Author  Svalina MN Year  2014
Journal  Cancer Cell Volume  26
Issue  2 Pages  154-5
PubMed ID  25117705 Mgi Jnum  J:214599
Mgi Id  MGI:5603463 Doi  10.1016/j.ccr.2014.07.011
Citation  Svalina MN, et al. (2014) YAPping about differentiation therapy in muscle cancer. Cancer Cell 26(2):154-5
abstractText  Overcoming a presumed differentiation block in the childhood muscle cancer embryonal rhabdomyosarcoma is often thought to hold promise as an approach to replace cytotoxic chemotherapy with molecularly-targeted differentiation therapies. In this issue of Cancer Cell, Tremblay and colleagues implicate YAP1 and the Hippo signaling pathway in the maintenance of differentiation-arrested and proliferative phenotypes for embryonal rhabdomyosarcoma.
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