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Publication : The GLU that holds cancer together: targeting GLUtamine transporters in breast cancer.

First Author  Moses MA Year  2015
Journal  Cancer Cell Volume  27
Issue  3 Pages  317-9
PubMed ID  25759015 Mgi Jnum  J:219922
Mgi Id  MGI:5629987 Doi  10.1016/j.ccell.2015.02.010
Citation  Moses MA, et al. (2015) The GLU that Holds Cancer Together: Targeting GLUtamine Transporters in Breast Cancer. Cancer Cell 27(3):317-9
abstractText  Many cancer cells require exogenous glutamine for proliferation, supply of TCA cycle intermediates, lipid synthesis, mTOR activity, and neutralization of reactive oxygen species. In this issue of Cancer Cell, Jeon and colleagues identify chemotherapy-induced endoplasmic reticulum stress as a novel strategy to target glutamine dependence.
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