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Publication : Charting the "Splice" Routes to MDS.

First Author  Obeng EA Year  2015
Journal  Cancer Cell Volume  27
Issue  5 Pages  607-9
PubMed ID  25965565 Mgi Jnum  J:221406
Mgi Id  MGI:5639137 Doi  10.1016/j.ccell.2015.04.016
Citation  Obeng EA, et al. (2015) Charting the "Splice" Routes to MDS. Cancer Cell 27(5):607-9
abstractText  Mutations in components of the 3' mRNA splicing machinery are found in almost 50% of myelodysplastic syndrome (MDS) cases. In this issue of Cancer Cell, Kim and colleagues, Colla and colleagues, and Shirai and colleagues report on the impact of mutated or dysregulated splicing factors to hematopoiesis, mRNA splicing, and MDS pathogenesis.
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