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Publication : Parsing Myc Paralogs in Oncogenesis.

First Author  Mathsyaraja H Year  2016
Journal  Cancer Cell Volume  29
Issue  1 Pages  1-2
PubMed ID  26766585 Mgi Jnum  J:231324
Mgi Id  MGI:5770192 Doi  10.1016/j.ccell.2015.12.009
Citation  Mathsyaraja H, et al. (2016) Parsing Myc Paralogs in Oncogenesis. Cancer Cell 29(1):1-2
abstractText  Myc and its paralog MycN are thought to be functionally redundant, but Myc- and MycN-driven medulloblastomas exhibit distinct phenotypes. In this issue of Cancer Cell, Vo and colleagues (2016) show that this phenotypic difference stems from the preferential ability of Myc, relative to MycN, to bind Miz1 and repress transcription.
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