| First Author | Fortin J | Year | 2016 |
| Journal | Cancer Cell | Volume | 29 |
| Issue | 4 | Pages | 429-431 |
| PubMed ID | 27070694 | Mgi Jnum | J:231823 |
| Mgi Id | MGI:5775226 | Doi | 10.1016/j.ccell.2016.03.020 |
| Citation | Fortin J, et al. (2016) Targeting PI3K Signaling in Cancer: A Cautionary Tale of Two AKTs. Cancer Cell 29(4):429-31 |
| abstractText | AKT inhibitors represent promising therapeutics for cancers with PI3K-AKT pathway hyperactivation. In this issue of Cancer Cell, Wang et al. (2016) report the unexpected finding that ablation of AKT signaling in hepatocytes leads to hepatocellular carcinoma and enhances the incidence of lung metastases in a toxin-induced liver cancer model. |
