| First Author | Guerit S | Year | 2016 |
| Journal | Cancer Cell | Volume | 29 |
| Issue | 4 | Pages | 427-429 |
| PubMed ID | 27070693 | Mgi Jnum | J:231824 |
| Mgi Id | MGI:5775227 | Doi | 10.1016/j.ccell.2016.03.024 |
| Citation | Guerit S, et al. (2016) Blood-Brain Barrier Breakdown Determines Differential Therapeutic Outcome in Genetically Diverse Forms of Medulloblastoma. Cancer Cell 29(4):427-9 |
| abstractText | Medulloblastoma driven by Wnt/beta-catenin and Sonic hedgehog pathway mutations show favorable and poor patient survival upon treatment, respectively. In this Cancer Cell issue, Phoenix and colleagues (2016) report disruption of the blood-brain barrier by Wif1 specifically in Wnt-driven medulloblastoma, resulting in increased treatment response and survival in mouse models. |
