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Publication : Pre-Metastatic Niche Formation Has Taken Its TOLL.

First Author  Kenific CM Year  2016
Journal  Cancer Cell Volume  30
Issue  2 Pages  189-191
PubMed ID  27505667 Mgi Jnum  J:234909
Mgi Id  MGI:5792430 Doi  10.1016/j.ccell.2016.07.012
Citation  Kenific CM, et al. (2016) Pre-Metastatic Niche Formation Has Taken Its TOLL. Cancer Cell 30(2):189-91
abstractText  Pre-Metastatic Niches (PMNs) result from communications between primary tumors and the microenvironment of future distant metastasis via tumor-derived factors. In this issue of Cancer Cell, Liu et al. show that TLR3 activation in lung epithelial cells by tumor exosomal RNAs triggers neutrophil recruitment, which contributes to PMN formation and metastasis.
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