First Author | Zeisig BB | Year | 2016 |
Journal | Cancer Cell | Volume | 30 |
Issue | 2 | Pages | 185-187 |
PubMed ID | 27505665 | Mgi Jnum | J:234910 |
Mgi Id | MGI:5792431 | Doi | 10.1016/j.ccell.2016.07.014 |
Citation | Zeisig BB, et al. (2016) Combinatorial Tethering: A Novel Mode to Recruit Non-canonical PRC1 for Normal and Malignant GC B Cell Development. Cancer Cell 30(2):185-7 |
abstractText | Polycomb repressive complexes (PRCs) are key to normal development and are frequently deregulated in human cancer. In this issue of Cancer Cell, Beguelin et al. report a mechanism of non-canonical PRC1 recruitment by BCL6 in collaboration with EZH2-mediated H3K27me3 for establishment of stable repressive complexes in germinal center B cells. |