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Publication : International harmonization of toxicologic pathology nomenclature: an overview and review of basic principles.

First Author  Mann PC Year  2012
Journal  Toxicol Pathol Volume  40
Issue  4 Suppl Pages  7S-13S
PubMed ID  22637736 Mgi Jnum  J:235852
Mgi Id  MGI:5803788 Doi  10.1177/0192623312438738
Citation  Mann PC, et al. (2012) International harmonization of toxicologic pathology nomenclature: an overview and review of basic principles. Toxicol Pathol 40(4 Suppl):7S-13S
abstractText  The International Harmonization of Nomenclature and Diagnostic Criteria for Lesions in Rats and Mice is a global project that is publishing criteria for both proliferative and nonproliferative changes in laboratory animals. This paper presents a set of general suggestions for terminology across systems. These suggestions include the use of diagnostic versus descriptive terms, modifiers, combination terms, and grading systems; and the use of thresholds, synonyms, and terminology for some processes that are common to several organ systems. The purpose of this paper is to help the reader understand some of the basic principles underlying the International Harmonization of Nomenclature and Diagnostic Criteria for Lesions in Rats and Mice process.
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