| First Author | Araya RE | Year | 2017 |
| Journal | Cancer Cell | Volume | 31 |
| Issue | 2 | Pages | 161-163 |
| PubMed ID | 28196588 | Mgi Jnum | J:239675 |
| Mgi Id | MGI:5829491 | Doi | 10.1016/j.ccell.2017.01.012 |
| Citation | Araya RE, et al. (2017) IFNAR1 Degradation: A New Mechanism for Tumor Immune Evasion?. Cancer Cell 31(2):161-163 |
| abstractText | Type I interferons have been shown to play a major role in anti-cancer immunity. In this issue of Cancer Cell, Katlinski et al. describe tumor-induced degradation of type I interferon receptor IFNAR1 chain as a new immune-evasion mechanism in colorectal cancers. Stabilizing IFNAR1 inhibits tumor growth and improves immunotherapy efficacy. |
