| First Author | Kumar S | Year | 2020 |
| Journal | Virusdisease | Pages | 1-6 |
| PubMed ID | 33283030 | Mgi Jnum | J:300410 |
| Mgi Id | MGI:6491842 | Doi | 10.1007/s13337-020-00637-4 |
| Citation | Kumar S, et al. (2020) Selection of animal models for COVID-19 research. Virusdisease :1-6 |
| abstractText | The researcher community across the globe is on a search for a promising animal model that closely mimics the clinical manifestation of SARS-CoV-2. Though some developments were seen such as serial adaptation in various animal species or the creation of genetically engineered models, a suitable animal model remains elusive. A model that could display the severity of human illness and can be used for the fast-track evaluation of potential drugs as well as for the clinical trials of vaccines is an urgent need of the hour. In the light of huge information generated on SARS-CoV-2 and daily updates received from the research community, we have chosen to review the current status of animal models of SARS-CoV-2 in encompassing the areas of viral replication, transmission, active/passive immunization, clinical disease, and pathology. The review is intended to help the researchers in the selection of appropriate animal models for SARS CoV-2 research in the fight against the current global pandemic. |
