| First Author | Kritzik MR | Year | 2010 |
| Journal | Endocrine | Volume | 37 |
| Issue | 2 | Pages | 312-21 |
| PubMed ID | 20960269 | Mgi Jnum | J:302332 |
| Mgi Id | MGI:6508129 | Doi | 10.1007/s12020-009-9297-5 |
| Citation | Kritzik MR, et al. (2010) Epithelial progenitor 1, a novel factor associated with epithelial cell growth and differentiation. Endocrine 37(2):312-21 |
| abstractText | The growth and renewal of epithelial tissue is a highly orchestrated and tightly regulated process occurring in different tissue types under a variety of circumstances. We have been studying the process of pancreatic regeneration in mice. We have identified a cell surface protein, named EP1, which is expressed on the duct epithelium during pancreatic regeneration. Whereas it is not detected in the pancreas of normal mice, it is found in the intestinal epithelium of normal adult mice, as well as during pancreatic repair following cerulein-induced destruction of the acinar tissue. The distinctive situations in which EP1 is expressed, all of which share in common epithelial cell growth in the gastrointestinal tract, suggest that EP1 is involved in the growth and renewal of epithelial tissues in both the intestine and the pancreas. |
