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CL Term : hepatic stellate cell [CL:0000632] Cell Ontology

Obsolete  false
description  A cell that is found in the perisinusoidal space of the liver that is capable of multiple roles including storage of retinol, presentation of antigen to T cells (including CD1d-restricted NKT cells), and upon activation, production of extracellular matrix components that can contribute to liver fibrosis. This activated state has a myofibroblast-like phenotype, though it's not clear in the literature if this is terminally differentiated. This cell type comprises approximately 8-15% of total cells in the liver.
  • synonyms:
  • vitamin A-storing cells,
  • Ito cell,
  • lipocyte,
  • fat-storing cell,
  • perisinusoidal cell,
  • hepatic perisinusoidal cell
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Ontology

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Ontology Term --> All descendants

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9 Expression

6 Samples