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CL Term : limbal epithelial stem cell of cornea [CL:4033093] Cell Ontology

Obsolete  false
description  A stem cell that is part of the corneo-scleral limbus. This cell type resides at the basal layer of the epithelium and has a small size and high nuclear to cytoplasmatic ratio (Secker and Daniels, 2009). A limbal stem cell is responsible for corneal epithelial renewal and repair (Li et al., 2023), and to help maintain a clear corneal surface by preventing conjunctival epithelial cells from migrating onto the cornea (Wang et al., 2023).
  • synonyms:
  • limbal stem cell,
  • LSC,
  • limbal epithelial stem cell,
  • LESC
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Ontology

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