| First Author | Leiter EH | Year | 1995 |
| Journal | Mouse Genome | Volume | 93 |
| Issue | 1 | Pages | 150 |
| Mgi Jnum | J:24316 | Mgi Id | MGI:72063 |
| Citation | Leiter EH (1995) Linkage of insulin promoter factor 1 (Ipf1) to Pmv12 and Actb on Chromosome 5. Mouse Genome 93(1):150 |
| abstractText | Full text of Mouse Genome contribution: Linkage of insulin promoter factor 1 (Ipf1) to Pmv12 and Actb on Chromosome 5. The insulin promoter factor 1 (Ipfl) gene (formerly somatostatin transcription factor 1) has been mapped to distal Chromosome 5 using The Jackson Laboratory BSS DNA mapping panel 2. A rat cDNA probe was kindly provided by Dr. Marc Montminy (The Salk Institute, La Jolla). A ~3.2 kb Sac1 restriciton fragment variant present in B6 and absent in M. spretus was typed by Southern blot in the (B6 x SPRET)Fl X SPRET DNA panel. The strain distribution pattern revealed linkage to markers on distal Chr. 5, with 0/93 recombinants with Pmv12 and 0/91 recombinants with Iapls3-9 (both proximal) and 2/92 recombinants with D5Bir22 and 6/94 recombinants with Actb (both distal). 1. Leonard J, Peers B, Johnson T, Ferreri K, Lee S, Montminy M. Characterization of somatostatin, transactivating factor-1, a novel homeobox factor that stimulates somatostatin expression in pancreatic islet cells. Mol. Endocrinol. 7:1275-1283, 1993. 2. Rowe L, Nadeau J, Turner R, Frankel W, Letts V, Eppig J, Ko M, Thurston S, Birkenmeier E. Maps from two interspecific backcross DNA panels as a community mapping resource. Mamm Genome 5:253-274, 1994. (E.H. Leiter) |
