| First Author | Derry JM | Year | 1989 |
| Journal | Cytogenet Cell Genet | Volume | 51 |
| Pages | 988 (Abstr.) | Mgi Jnum | J:12527 |
| Mgi Id | MGI:60772 | Citation | Derry JM, et al. (1989) Localization of the Ccg1 gene on the mouse X Chromosome. Cytogenet Cell Genet 51:988 (Abstr.) |
| abstractText | Full text of Abstract: Localization of the Ccg1 gene on the mouse X chromosome. (A2364) JMJ Derry, PJ Barnard. MRC Molecular Neurobiology Unit, MRC Centre, Cambridge, CB2 2QH, England. The human CCGl gene, which complements the temperature-sensitive hamster cell cycle mutations BN462 and ts13, has recently been cloned and shown to be located on the X chromosome. Using pedigree breakpoint analysis in a mouse interspecies backcross we have been able to localize the mouse Ccg1 gene on the X chromosome, relative to seven other gene markers. We have found that Ccg1 maps in the Ar - Pgk-1 interval. In 51 animals studied, Ccg1 is found to co-segregate with indicating tight linkage of these two loci. These data give the gene order: cen - Cybb - Hprt - mdx - Zfx - Ar - Ccg1/Pgk-1 - tel Further, our data would position the human locus CCGl to the long arm of the human X chromosome at Xq11-q13, assuming conservation of gene orders, and is in agreement with published mapping data. |
