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Publication : Gene order of Chy-vt-Re on Chromosome 11

First Author  Lyon MF Year  1986
Journal  Mouse News Lett Volume  74
Pages  96 Mgi Jnum  J:14080
Mgi Id  MGI:62257 Citation  Lyon MF, et al. (1986) Gene order of Chy-vt-Re on Chromosome 11. Mouse News Lett 74:96
abstractText  Full text of MNL contribution: 5. Gene order of Chy-vt-Re on chromosome 11. Chylous ascites (Chy) was previously shown to be closely linked to vt on chromosome 11 (MNL 72: 106-107). Further data, involving 3-point backcrosses with Chy, vt and Re, and also crosses of Chy to wa-2, now indicate that Chy is proximal to vt. From crosses of Chy+Re/+vt+ x +vt+/+vt+ the data are Sex of het.: female; Chy+Re: 12; +vt+: 18; Chy++: 4; +vtRe: 16; ++Re: 3; Chyvt+: -; +++: -; Sex of het.: male; Chy+Re: 30; +vt+: 49; Chy++: 7; +vtRe: 14; ++Re: 4; Chyvt+: 3; +++: 1. In addition data from 2-point backcrosses of Chy++Re were Sex of het.: female; Chy+: 17; +Re: 28; ++: 12; ChyRe: 7; Sex of het.: male; Chy+: 67; +Re: 108; ++: 38; ChyRe: 30. and a cross of Chy+/+wa-2 x wa-2/wa-2 (male het.) gave 4 recombinants out of 32 offspring. The R.F.s therefore are wa-2-Chy: male: 4/32; R.F. (%): 12.5 +/- 5.8; Chy-vt: male: 8/108; R.F. (%): 7.4 +/- 2.5; female: 3/53; R.F. (%): 5.7 +/- 3.2; Chy-Re: male: 96/351; R.F. (%): 27.4 +/- 2.4; female: 42/117; R.F. (%): 35.9 +/- 4.4. (Lyon, Glenister)
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