| First Author | Zhu Y | Year | 2003 |
| Mgi Jnum | J:84607 | Mgi Id | MGI:2668494 |
| Citation | Zhu Y, et al. (2003) Histone Genes: Associate Sequences and Biological information with the appropriate Genes. |
| abstractText | The five classes of replication-dependent histone genes have been identified from the human and mouse genome assembly sequences and systematically named by W. F. Marzluff et al. Genomic sequences represent each gene were derived from the genome sequences and deposited in GenBank. The replication-dependent histone genes encoding mRNAs lack a ply(A) tail and introns are organized in one major cluster (Hist1) and three minor clusters (Hist2, Hist3 and Hist4). In addition to the replication-dependent histone genes, there are also several cell-cycle independent replacement variant genes encode polyadenylated mRNAs for H1, H2a, and H3. There has never been systematical nomenclature for the different non-allelic copies of the histone genes, which were named arbitrarily as they were discovered. Some of the sequences provided by W. F. Marzluff et al in their paper are problematic. We analyzed all the histone related sequences from GenBank to ensure appropriate sequence-to-gene associations. The biological information and references associated with histone genes were checked for correctness. |
