| First Author | Hsieh CL | Year | 1991 |
| Journal | Mamm Genome | Volume | 1 |
| Issue | Suppl | Pages | S522 (Abstr.) |
| Mgi Jnum | J:30763 | Mgi Id | MGI:78363 |
| Citation | Hsieh CL, et al. (1991) Mouse gene for tenascin (hexabrachion) on Chromosome 4. Mamm Genome 1(Suppl):S522 (Abstr.) |
| abstractText | Full text of Abstract: 41. MOUSE GENE FOR TENASCIN (HEXABRACHION) ON CHROMOSOME 4. C.-L. Hsieh1, U. Dorries2, M. Schachner2 and U. Francke1,3. 1Howard Hughes Medical Inst., Stanford CA, 2Dept. Neurobiology, Heidelberg University Germany, 3Depts. Genetics & Pediatrics, Stanford University Medical School, Stanford CA. The human gene for the large extracellular matrix protein tenascin, also known as hexabrachion, J1 glycoprotein, cytotactin, myotendinous antigen or glioma mesenchymal extracellular matrix antigen (gene symbol HXB) has been assigned to 9q32-qter (Gulcher et al., Genomics 6: 616, 1990). Southern blot analysis of rodent x mouse somatic cell hybrids, using a murine 2 kb cDNA probe, has allowed us to map the mouse homolog Hxb to MMU4. No polymorphism was found with BamHI, BglII, HindIII, HincII, PvuII, PstI, KpnI and EcoRI in the five inbred strains AKR/J, C3H/HeJ, C57BL/6J, C57L/J and DBA/2J tested. HXB/Hxb thus joins the conserved syntenic group of ORMl/Orm-1 and ALAD/Lv on HSA9q34/MMU4C. At least six other genes on distalHSA9q are homologous to loci on MMU2. |
