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Allele : Brca2<tm1Brn> breast cancer 2, early onset; targeted mutation 1, Anton Berns
Primary Identifier  MGI:2156556 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Brca2
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  LoxP sites were inserted flanking exon 11 by homologous recombination. Subsequent Cre-mediated recombination in ES cells excised an adjacent PGK-neomycin and thymidine kinase cassette prior to the production of chimeric mice.
  • mutations:
  • Insertion
  • synonyms:
  • Brca2<F11F>,
  • Brca2<F11F>,
  • Brca2<F11>,
  • Brca2<F11>,
  • Brca2<LoxP>,
  • Brca2<LoxP>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Genotypes/models

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

4 Carried By

0 Driven By

52 Publication categories





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