| First Author | Reeves RH | Year | 1989 |
| Journal | Cytogenet Cell Genet | Volume | 51 |
| Pages | 1064 (Abstr.) | Mgi Jnum | J:12503 |
| Mgi Id | MGI:60748 | Citation | Reeves RH, et al. (1989) Localization on mouse chromosome 16 of Smst and Gap43: a conserved synteny with human chromosome 3. Cytogenet Cell Genet 51:1064 (Abstr.) |
| abstractText | Full text of Abstract: Localization on mouse chromosome 16 of Smst and Gap43: A conserved synteny with human chromosome 3. (A2578). RH Reeves, BF O'Hara, JD Gearhart. Department of Physiology, Johns Hopkins University School of Medicine, Baltimore, MD 21205 USA. A conserved synteny has been demonstrated previously between mouse chromosome 16 (MMU 16) and human chromosome 3 which includes the genes encoding preprosomato- statin (Smst/SST) and the nerve growth-related peptide, Gap43 (Gap43/ GAP43) [Kosick et al., Neuron 1:127]. The recombination frequency between these sequences measured on four different backcrosses is 49/431 (.114 +/- .005). Smst is located 13 cM from the centromere on MMU 16. Gap43 is 15-20 cM from the proximal end of the region of conserved synteny between MMU 16 and human chromosome 21. MMU 16 is known to contain genes found on 4 human chromosomes, and genes on HAS 21 are found on at least three mouse chromosomes. A comparative map is presented. |
