First Author | Festing MFW | Year | 1987 |
Journal | Mouse News Lett | Volume | 79 |
Pages | 19 | Mgi Jnum | J:24742 |
Mgi Id | MGI:72471 | Citation | Festing MFW (1987) ABP through AM Strains. Mouse News Lett 79:19 |
abstractText | Full text of MNL contribution: ABP Inbr (Le) 64. Pink-eyed-fawn: a,b,bt,p,se. Origin: A,B.Griffen to Lane 1968. Sib-mated since then. Useful for linkage testing. Also carries wa-1. Maint. by Le ACR Inbr ?. Albino. Origin. AKR substrain to CIBA 1949. Known as AKR/FuA. Genetic contamination in 1953 (see AKR), renamed ACR. Maint. by A. AE Inbr (Nctr) 80. Pink-eyed fawn: ae, b,d,p, se. Origin: Two litters of stock 3H-220 from Hollander, Iowa to Inst. Cancer Research, PA in 1962 at about F3. To Nctr in 1972. Caesarian-derived and fostered to C3Hf in 1980. Markedly lower electroconvulsive thresholds without increased susceptibility to seizures induced by pentylenetetrazol. Low responsiveness to Phenobarbital and valproic acid. Maint. by Nctr AEJ Inbr (Rk) 70.Black. ae. Origin: Hollander, Iowa. Ames waltzer stock with miscellanenous markers to M.C.Green 1963. Crossed once to C57BL/10 followed by cross to C57BL/6-AW-J, then b x s. To Roderick 1972. Maintained by Rk. AG Inbr (Cam) c155. Colour depends on genotype Ay/ae x Ay/ae with Aw, A, As, at, a and p continuously backcrossed to the Ay/ae Line. Origin: R.A.Fisher, 'A' from Gruneberg in 1945 at F34 (a CBA substrain, J.R. Morton, unpublished communication). Various alleles introduced by M.E.Wallace by backcrossing and maintained mainly by sib-mated substrain until 1959, then backcrossing to a single Ay/a substrain, then Ay/ae substrain. Non-sibmating in a very small stock for 23 generations. Stock now frozen except for close inbreeding of Aw, at and ae. Maint. by Cam. AKR Albino: a,B,c. Origin: a dealer named Detwiler in Norristown PA. Carried by Furth as a high-leukaemia strain from 1928 to 1936, then random bred at the Rockefeller Inst. for several generations. b x s by Mrs. Rhoades to F9 then C.Lynch to F21. This strain is best known for it's high incidence of lymphatic Leukaemia, and for the Thy-1a T- cell antigen, which is only present in this and a few other strains. Three major substrains were split off in 1940 including: AKR/J Inbr ?. To Jackson Laboratory 1940. Maintained by J. AKR/LwN Inbr ?. To Law 1940, to N 1956 at F53. Maint. by N. AKR/FuA see ACR/A. Maint. by A. AKR/Cum Inbr ?. Origin ?. Differs from other substrains in being Mod-1a. AKXL- Set of 18 recombinant inbred strains. Inbr 15-40+. Origin: B.A.Taylor from a cross between AKR/J and C57L/J. Maint. by Ty. AL Inbr (N) 195. Albino:a,b,c. Origin: Believed to have originated from a strain A outcross to unknown strain followed by b x s mating, but should not be considered a substrain of A. Maint. by N. AM Inbr (Nctr) 63. Mottled yellow, mottled agouti: Avy/am, am/am. Origin: am/am males from L.B.Russell, Oak Ridge Nat.Lab. in 1965 at F5 to the Inst. of Cancer Research, PA. Mated by Avy/a females (F12) of strain VY/Wf. To Nctr |