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Publication : Sensory origin of visually evoked activity in auditory cortex.

First Author  Olsen T Year  2025
Journal  Cell Rep Volume  44
Issue  10 Pages  116364
PubMed ID  41032413 Mgi Jnum  J:381102
Mgi Id  MGI:8253917 Doi  10.1016/j.celrep.2025.116364
Citation  Olsen T, et al. (2025) Sensory origin of visually evoked activity in auditory cortex. Cell Rep 44(10):116364
abstractText  Cross-modal responses are common in primary sensory cortex, yet a recent study showed that signals in primary visual cortex (V1) once labeled multisensory were instead more closely related to face movements. To what extent can multisensory processing in other modalities also be explained by face movements? We measured face movements and neural activity in awake mouse primary auditory cortex (A1) and V1 in response to visual and auditory stimulation as well as during spontaneous activity. We find that visual stimuli rarely evoke face movements, A1 responses to visual input remain robust even in the absence of face movement, and optogenetic silencing of V1 reduces A1 visual responses. Taken together, these results confirm that cross-modal responses in the auditory system are primarily sensory, not state driven, in origin.
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