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Allele : Gt(ROSA)26Sor<em1(CAG-Tfeb*)Lusu> gene trap ROSA 26, Philippe Soriano; endonuclease-mediated mutation 1, Lu Sun
Primary Identifier  MGI:8242767 Allele Type  Endonuclease-mediated
Attribute String  Conditional ready Gene  Gt(ROSA)26Sor
Strain of Origin  C57BL/6J Is Recombinase  false
Is Wild Type  false
molecularNote  Using CRISPR/Cas9 endonuclease-mediated genome editing, a guide RNA [ACUCCAGUCUUUCUAGAAGA] was selected to introduce a CMV-IE enhancer/chicken beta-actin/rabbit beta-globin hybrid promoter (CAG), followed by a loxP-flanked STOP cassette, a Halo-tagged transcription factor EB sequence, harboring the S141A and S210A mutations, into the Gt(ROSA)26Sor locus.
  • mutations:
  • Insertion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

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