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Allele : Gt(ROSA)26Sor<em5Mvw> gene trap ROSA 26, Philippe Soriano; endonuclease-mediated mutation 5, Michael Wiles
Primary Identifier  MGI:6160836 Allele Type  Endonuclease-mediated
Attribute String  RMCE-ready Gene  Gt(ROSA)26Sor
Inheritance Mode  Not Specified Strain of Origin  NOD.Cg-Prkdc<scid> Il2rg<tm1Wjl>/SzJ
Is Recombinase  false Is Wild Type  false
molecularNote  CRISPR/cas9 genome editing used guide RNAs to target intron 1 of the Gt(ROSA)26Sor locus. Oligonucleotide donor DNAs were created encoding a duel landing pad flanked by the heterologous attP attachment sites - specifically a 48 bp Bxb1 attP-GT sequence, a 240 bp spacer of native Gt(ROSA)26Sor sequence and a 48 bp Bxb1 attP-GA sequence.
  • mutations:
  • Insertion
  • synonyms:
  • NSG.Bxb1v2,
  • NSG.RosaBxb-GT/GA,
  • NSG.RosaBxb-GT/GA,
  • NSG.Bxb1v2
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Genotypes/models

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

3 Publication categories





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