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Allele : Gt(ROSA)26Sor<tm2(CAG-COP4*/mCherry)Ksak> gene trap ROSA 26, Philippe Soriano; targeted mutation 2, Kenji Sakimura
Primary Identifier  MGI:8421670 Allele Type  Targeted
Attribute String  Conditional ready, Reporter Gene  Gt(ROSA)26Sor
Transmission  Germline Strain of Origin  C57BL/6NCrlCrlj
Is Recombinase  false Is Wild Type  false
molecularNote  Transgenic mice carry a construct knocked into the Gt(ROSA)26Sor locus, consisting of a CAG promoter, and frt-flanked pgk-Neo cassette, a STOP cassette consisting of the terminator of the yeast His3 gene and SV40 poly-adenylation sequence, cDNA encoding channelrhodopsin-2 (mutation H134R) cDNA tagged with mCherry at the C-terminus, a woodchuck hepatitis virus post-transcriptional regulatory element, and the rabbit beta-globin poly-adenylation sequence. Two loxP sites were inserted before the frt-Neo cassette and after the STOP cassette.
  • mutations:
  • Insertion
  • synonyms:
  • Rosa26- floxed-STOP hChR2 (H134R)-mCherry,
  • Rosa26- floxed-STOP hChR2 (H134R)-mCherry
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

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